ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-10-18

Cytomegalovirus-Induced Hepatitis in an Immunocompetent Patient

Prashant Gupta, Madhu Suryadevara, Avash Das

(Department of Internal Medicine, Louisiana State University Health Sciences Center – University Hospital and Clinics, Lafayette, USA)

Am J Case Rep 2014; 15:447-449

DOI: 10.12659/AJCR.890945


Background: Hepatitis is a descriptive term given for any inflammation of the liver. It can be characterized as inflammatory cells infiltrating normal hepatic parenchyma, which destroys their ability to perform normal physiologic functions. Hepatitis is a common disorder in immunocompetent populations, mainly attributed to viruses, alcohol, drugs, or autoimmune causes.
Case Report: Cytomegalovirus is a virus mostly affecting immunocompromised patients, resulting in infectious mononucleosis-like symptoms as well as hepatitis in liver transplant patients, but is generally benign in immunocompetent hosts. This report presents an unusual case of hepatitis caused by Cytomegalovirus in an immunocompetent patient with previous Herpes Simplex virus infection. A 20-year-old African-American woman presenting with intermittent subjective fevers and chills, sore throat, non-productive cough, and decreased appetite 1 month ago was diagnosed with a case of Cytomegalovirus-induced hepatitis.
Conclusions: This report clearly emphasizes the need for investigation of other disease entities such as Cytomegalovirus as a potential cause of hepatitis in an immunocompetent patient after more common causes of hepatitis have been ruled out.

Keywords: Cytomegalovirus Infections, Fever, Hepatitis, Viral, Human




Published: 2014-10-15

Long-term Survival after Surgical Treatment of Metachronous Bilateral Adrenal Metastases of Non-small Cel...


Naohiro Taira, Tsutomu Kawabata, Takaharu Ichi, Kazuaki Kushi, Tomofumi Yohena, Hidenori Kawasaki, Kiyoshi Ishikawa

Am J Case Rep 2014; 15:444-446

DOI: 10.12659/AJCR.891027

Published: 2014-10-12

A Case of Intracranial Hemorrhage Caused by Combined Dabrafenib and Trametinib Therapy for Metastatic Mel...


Le Min Lee, Lynn Feun, Yaohong Tan

Am J Case Rep 2014; 15:441-443

DOI: 10.12659/AJCR.890875