ISSN 1941-5923


Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more

Published: 2014-08-17

Metastatic Hepatocellular Carcinoma to Parotid Glands

Abdel-Naser Elzouki, Hisham Elkhider, Khalid Yacout, Ahmed Al Muzrakchi, Shaikah Al-Thani, Omer Ismail

(Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar)

Am J Case Rep 2014; 15:343-347

DOI: 10.12659/AJCR.890661

Background: Hepatocellular carcinoma is a common cancer, but it rarely metastasizes to the salivary glands. A review of the literature revealed only 5 reported cases of hepatocellular carcinoma metastatic to parotid glands. We here report an additional case of this rare association.
Case Report: A 66-year-old male with a background of type 2 diabetes mellitus and post-alcoholic decompensated liver cirrhosis presented with a progressively enlarging painful right facial swelling for 2 months that was eventually found to be due to hepatocellular carcinoma metastatic to the right parotid gland. Fine needle aspiration from the right parotid showed sheets and single malignant cells that were interpreted as carcinoma not otherwise specific. However, biopsy showed metastatic hepatocellular carcinoma into the right parotid gland.
Conclusions: We report an additional case of the rare metastasis of hepatocellular carcinoma to the parotid glands. It should therefore be considered in a patient with decompensated liver cirrhosis presenting with a parotid swelling. Furthermore, the present case demonstrates the importance of the tissue biopsy for obtaining an accurate final diagnosis.

Keywords: Carcinoma, Hepatocellular, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasm Metastasis, Parotid Gland

Published: 2014-08-14

Fibroepithelial Polyp of the Epiglottis

Zainab Farzal, Seckin O. Ulualp, Dinesh Rakheja

Am J Case Rep 2014; 15:340-342

DOI: 10.12659/AJCR.890924

Published: 2014-08-11

Utility of the Serum ProGRP Level for Follow-up of Pulmonary Carcinoid Tumors

Naohiro Taira, Tsutomu Kawabata, Takaharu Ichi, Kazuaki Kushi, Tomofumi Yohena, Hidenori Kawasaki, Kiyoshi Ishikawa, Seiya Kato

Am J Case Rep 2014; 15:337-339

DOI: 10.12659/AJCR.890692