ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-10-21

Prolonged Ventricular Asystole: A Rare Adverse Effect of Hydrocodone Use

Sivakumar Sudhakaran, Saherish S. Surani, Salim R. Surani

(Department of Medicine, Texas A&M University Health Science Center, College Station, USA)

Am J Case Rep 2014; 15:450-453

DOI: 10.12659/AJCR.891214


Background: Prolonged ventricular asystole is a rare vagal reaction caused by hydrocodone use. Sinus bradycardia is a characteristic presentation of the vasovagal response; examples of other presentations include arrest or atrioventricular block. Physicians need to be aware of ventricular asystole due to vagally-mediated atrioventricular block caused by hydrocodone or other opiates.
Case Report: We present a case of prolonged ventricular asystole in a young patient due to a vasovagal reaction caused by the hydrocodone found in the hydrocodone/acetaminophen combination.
Conclusions: Ventricular asystole can be a rare complication of hydrocodone found in hydrocodone/acetaminophen. Physicians need to be aware of this adverse effect, rather then resorting to expensive diagnostic interventions.

Keywords: Arrhythmias, Cardiac, Heart Arrest, Heart Arrest




Published: 2014-10-18

Cytomegalovirus-Induced Hepatitis in an Immunocompetent Patient


Prashant Gupta, Madhu Suryadevara, Avash Das

Am J Case Rep 2014; 15:447-449

DOI: 10.12659/AJCR.890945

Published: 2014-10-15

Long-term Survival after Surgical Treatment of Metachronous Bilateral Adrenal Metastases of Non-small Cel...


Naohiro Taira, Tsutomu Kawabata, Takaharu Ichi, Kazuaki Kushi, Tomofumi Yohena, Hidenori Kawasaki, Kiyoshi Ishikawa

Am J Case Rep 2014; 15:444-446

DOI: 10.12659/AJCR.891027