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American Journal of Case Reports have been selected for the ESCI - Emerging Sources Citation Index (Thomson Reuters, Web of Science, ISI), launching in November of 2015 as a new edition of the Web of Science.

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Published: 2016-06-29

A Rare Case of Ascites due to Peritoneal Amyloidosis

Fernanda Stofer, Maria Fernanda Barretto, Ana Luisa Gouvea, Mario Ribeiro, Marcio Neves, Ronaldo Altenburg Gismondi, Luís Otavio Mocarzel

(Department of Clinical Medicine, Fluminense Federal University, Niterói, Brazil)

Am J Case Rep 2016; 17:439-443

DOI: 10.12659/AJCR.898357


BACKGROUND: The clinical manifestations of amyloidosis depend on the type of insoluble protein as well as the location of amyloid deposits in tissues or organs. In the gastrointestinal tract, the small intestine is the most common site of amyloid deposits, whereas peritoneal involvement and ascites are rare.
CASE REPORT: We report on a case of ascites due to peritoneal amyloidosis. A 65-year-old patient was admitted to our institution due to anasarca and pulmonary congestion, mimicking heart failure. We started the patient on diuretics and vasodilators. Despite improvement in pulmonary congestion and peripheral edema, his ascites was not reduced. Echocardiogram revealed restrictive cardiomyopathy and a speckle-tracking pattern suggestive of cardiac amyloidosis. Subcutaneous and peritoneal biopsies revealed amyloidosis.
CONCLUSIONS: Amyloidosis is rare in the peritoneum and is usually asymptomatic. Ascites occurs in only 20% of patients with peritoneal amyloidosis. We searched PubMed using “ascites” and “amyloidosis” and identified only eight case reports of amyloidosis with ascites. Physicians should be particularly careful in heart failure and anasarca cases when ascites is disproportional or not responsive to diuretic treatment. To date, there is no specific treatment for peritoneal amyloidosis.

Keywords: Amyloidosis, Ascites, Heart Failure, Peritoneal Diseases




Published: 2016-06-27

Successful Treatment of Pyoderma Gangrenosum with Cryoglobulinemia and Hepatitis C


Mohsen Pourmorteza, Fady Tawadros, Gilbert Bader, Mohamed Al-Tarawneh, Emilie Cook, Wael Shams, Mark Young

Am J Case Rep 2016; 17:434-438

DOI: 10.12659/AJCR.898611

Published: 2016-06-25

Subcutaneous Panniculitis-like T Cell Lymphoma Mimicking Early-Onset Nodular Panniculitis


Guifen Shen, Lingli Dong, Shengtao Zhang

Am J Case Rep 2016; 17:429-433

DOI: 10.12659/AJCR.898021