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Diagnostic and therapeutic difficulties in secondary amyloidosis

Krystian Adrych, Jacek Wierzbowski, Grażyna Rompa, Kazimierz Jaśkiewicz, Sylwia Raczyńska, Robert Rzepko, Andrzej Kryszewski

CaseRepClinPractRev 2004; 5:511-515

ID: 428988


Background: The hallmark of amyloidosis is tissue deposition of a featureless substance called amyloid. Amyloidosis can be congenital or acquired, localized or generalized. Case Report: We present a case of a 22-year-old man, previously treated for gluten enteropathy and Crohn’s disease, in whom we diagnosed a secondary amyloidosis from an unknown cause. The diagnosis was confirmed microscopically. The treatment of our patient was unsuccessful, and the disease process led to death. Conclusions: Secondary amyloidosis with gastrointestinal tract involvement is rare, but in spite of progress in medical science its diagnosis and treatment poses significant problems.

Keywords: Amyloidosis, Crohn Disease, gluten enteropathy