01 September 2003
Bone marrow supression and acute renal failure related to single dose of 500 miligram dipyrone
Kürsad Erinc, Murat Aslan, Filiz Aslan, Cengiz Beyan, Ertan Demirtas FaccCase Rep Clin Pract Rev 2003; 4(2):94-96 :: ID: 429041
Abstract
Background: Nonsteroid anti-inflammatory drugs may cause idiosyncrasy in some susceptible individuals. This case is presented in order to make an impact on a rare form of dipyrone-associated idiosyncrasy.Case Report: A 68-year-old female was hospitalized with dyspnea, pretibial edema and fatigue. Initial complete blood count, hepatic and renal functions were normal. On 4th day of her hospitalization, she was given 500 mg dipyrone because she suffered toothache. In the following days, moderate decrement of the blood cells (WBC: 2.0i103/KL, RBC: 3.00i106/KL, Hb: 9.2 g/dl, Htc: 28%, Platelets: 82i103/KL) and further abnormality of renal function (BUN: 124 mg/dl, creatinine: 7.0 mg/dl) were encountered. On 9th day, renal functions were normal (BUN: 35 mg/dl, creatinine: 0.9 mg/dl). At that time, complete blood count values were as follows: Hb: 9.8 g/dl, Htc: 30.3%, WBC: 5.1i103/KL, Platelets: 237i103/KL. Conclusions: Dipyrone-associated idiosyncrasy may result serious abnormalities in renal and hemopoetic functions. Therefore, using dipyrone must require attention in certain situations.
Keywords: bone marrow suppression, Dipyrone, Idiosyncrasy
61
In Press
19 Mar 2024 : Case report
Bilateral Simultaneous Basal Ganglia Hemorrhage: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943174
19 Mar 2024 : Case report
Medial Hoffa Fracture: A Case Report and Literature Review of Approach and ManagementAm J Case Rep In Press; DOI: 10.12659/AJCR.943136
21 Mar 2024 : Case report
Pediatric Neurogenic Pulmonary Edema After Brain Tumor Removal Complicated with Severe Myocardial Injury: A...Am J Case Rep In Press; DOI: 10.12659/AJCR.943645
21 Mar 2024 : Case report
Chlamydia psittaci Pneumonia: Diagnosis, Treatment, and Challenges in the Context of COVID-19Am J Case Rep In Press; DOI: 10.12659/AJCR.942921
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250