Ebrahim Razi, Abdolhossein Davoodabadi, Tahereh Khamehchian
CaseRepClinPractRev 2006; 7:244-247
Background: Primary mediastinal seminomas are uncommon, representing only 2 to 4 percent of all mediastinal masses, which are usually located in the anterior mediastinum, and predominantly occur in
young males between the ages of 20 and 40.
Case Report: Herein a case of mediastinal seminoma presenting with superior vena cava obstruction is reported. A 34 years old man was evaluated for complaints of dyspnea and edematous face and neck.
Chest radiography and computerized tomography revealed an anterior superior mediastinal
mass. The diagnosis was made by thoracotomy and histologically, the tumor was diagnosed as a seminoma.
Postoperative chemotherapy was performed, that was consisted of four-course cisplatin-containing
combination. Our case is alive in good health for 16 months after treatment and good prognosis will be expected.
Conclusions: This article describes a case of primary mediastinal seminoma in a young male, which presenting
with superior vena cava syndrome that underwent to remission and improvement with cisplatinbase
Keywords: mediastinal seminoma, Superior Vena Cava Syndrome, Cisplatin