24 April 2008
Acute hepatitis E with coexistent Plasmodium falciparum infection in a patient with a history of foreign travel
Jeffrey Turner, Chin lye Ch’ngAm J Case Rep 2008; 9:252-254 :: ID: 855039
Abstract
Background: Hepatitis E and malaria are infectious diseases endemic in India and other parts of the world. Both can result in varying degrees of hepatic impairment. There is also an increasing awareness of sporadic hepatitis E within the United Kingdom. This report presents the case of a young gentleman with hepatitis E & Plasmodium falciparum infections. It highlights that these two diseases may coexist in the same patient, complicating their initial presentation. We provide an overview of both hepatitis E and malarial infections, with their impact upon certain patient groups within the UK and abroad.
Case Report: A previously well 17-year-old gentleman was admitted with an intermittent pyrexia after travel from India. Deranged liver function tests were noted following admission, which were initially attributed to a Plasmodium falciparum malaria infection. However his liver function continued to decline despite appropriate treatment of this infection and an improving parasitaemia. After further investigation he was diagnosed with a coexisting acute hepatitis E infection. His clinical condition gradually improved with conservative treatment. He was later discharged home and has remained well at follow up.
Conclusions: Several infectious diseases may coexist in a patient complicating their presentation and management. If a patient does not improve clinically or biochemically with appropriate treatments, then additional diagnoses should be considered. Malaria may be successfully prevented and treated with appropriate drug therapy, reducing mortality rates. Hepatitis E & malaria should always be considered in immigrants or travellers returning from endemic areas presenting with a pyrexia or deranged liver function tests.
Keywords: Hepatitis E, Plasmodium falciparum, Malaria, liver dysfunction
In Press
30 Jan 2024 : Case report
Successful Anesthetic Management for Obese Patients with Interstitial Lung Disease Undergoing Laparoscopic ...Am J Case Rep In Press; DOI: 10.12659/AJCR.942736
14 Mar 2024 : Case report
Bilateral Low-Flow Type-D Dural Carotid-Cavernous Fistula: Diagnosis and Treatment with 3D Time-of-Flight M...Am J Case Rep In Press; DOI: 10.12659/AJCR.942833
31 Jan 2024 : Case report
Gaucher Disease Coexisting with Cytomegalovirus Infection: A Rare Presentation in an InfantAm J Case Rep In Press; DOI: 10.12659/AJCR.943398
31 Jan 2024 : Case report
Unconjugated Hyperbilirubinemia in Acetaminophen-Related Acute Liver FailureAm J Case Rep In Press; DOI: 10.12659/AJCR.942703
Most Viewed Current Articles
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
05 Mar 2022 : Case report
Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...DOI :10.12659/AJCR.935336
Am J Case Rep 2022; 23:e935336
02 Apr 2022 : Case report
Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...DOI :10.12659/AJCR.935743
Am J Case Rep 2022; 23:e935743