24 July 2008
4 A Syndrome
Sujoy Ghosh, Debmalya Sanyal, Sarmistha Mukherjee, Moutusi Raychowdhuri, Satinath Mukherjee, Subhankar ChowdhuryAm J Case Rep 2008; 9:329-332 :: ID: 865123
Abstract
Background: Allgrove syndrome is a rare inherited familial disorder with variable age of onset and presentation. It is usually diagnosed in the first decade of life with features of primary adrenal insufficiency characterized by hypoglycaemic seizures, shock and pigmentation. Less frequently, a child may be present with dysphagia due to achalasia or with ocular symptoms of dry eyes. Manifestations in adult patients are rarely reported.
Case Report: We report a case of an 18-year-old boy with undiagnosed adrenal insufficiency and neurological problems associated with deficient tear secretion (alacrima) and asymptomatic achalasia.
Conclusions: This case highlights the spectrum of abnormalities associated with Allgrove syndrome and that the diagnosis of Allgrove syndrome should be considered in all patients presenting with any one of the classic symptoms. Other features, even if asymptomatic should be explored.
Keywords: adrenal insufficiency, achalasia, alacrima, adrenal myeloneuropathy
In Press
17 Mar 2024 : Case report
Rare Presentation of Rapidly Involuting Congenital Hemangioma of the Skull: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943370
18 Mar 2024 : Case report
Perineal Benign Symmetric Lipomatosis in a Female Patient: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943803
18 Mar 2024 : Case report
Successful Endovascular Microembolization for Post-Traumatic High-Flow Priapism: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943467
19 Mar 2024 : Case report
Jejunal Diverticulosis Causing Small Intestinal Volvulus and Closed Loop ObstructionAm J Case Rep In Press; DOI: 10.12659/AJCR.943376
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250