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A Case of Neuro-Behcet’s Disease Presenting with Central Neurogenic Hyperventilation

Ayham M. Alkhachroum, Saba Saeed, Jaspreet Kaur, Tanzila Shams, Michael A. DeGeorgia

(Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH, USA)

Am J Case Rep 2016; 17:154-159

DOI: 10.12659/AJCR.895382

Published: 2016-03-11

BACKGROUND: Behcet’s disease is a chronic inflammatory disorder usually characterized by the triad of oral ulcers, genital ulcers, and uveitis. Central to the pathogenesis of Behcet’s disease is an autoimmune vasculitis. Neurological involvement, so called “Neuro-Behcet’s disease”, occurs in 10-20% of patients, usually from a meningoencephalitis or venous thrombosis. 
CASE REPORT: We report the case of a 46-year-old patient with Neuro-Behcet’s disease who presented with central neurogenic hyperventilation as a result of brainstem involvement from venulitis.
CONCLUSIONS: To the best of our knowledge, central neurogenic hyperventilation has not previously been described in a patient with Neuro-Behcet’s disease.

Keywords: Behcet Syndrome - diagnosis, Alkalosis, Respiratory - etiology, Brain Diseases - diagnosis, Brain Stem - blood supply, Female, Humans, Hyperventilation - etiology, Magnetic Resonance Angiography, Middle Aged, Respiratory Distress Syndrome, Adult - etiology