Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

02 January 2005 : Original article  Hungary

Frontal lobe dysfunction secondary mania and dementia syndrome following right posterior cerebral artery territory infarction

Nages Nagaratnam, Kujan Nagaratnam

Case Rep Clin Pract Rev 2005; 6:35-40 :: ID: 16406

Abstract

Summary
Background: The clinical manifestations of an acute stroke could be well circumscribed and or widespread producing a number of variants. The clinical features could be diverse and complex depending
on the site, extent and location of the lesion. The possibility of frontal lobe disorder (or extensive behavioural dysfunction) in posterior cerebral artery territory infarction has often been overlooked
in most reports, probably because it does not fit well with the fact that the frontal lobe is typically spared in posterior cerebral artery infarction.
Case Report: This case study is about a 78- year- old right- handed man previously well who suffered a right posterior cerebral artery infarction. The first presenting symptoms were confusion, subtle weakness of the left side and contra- lateral homonymous hemianopia. This was followed a few days later by complex visual and auditory hallucinations, complex motor behaviour (environmental driven responses and utilization behaviours), disinhibition, aspontaniety, marked perseveration and visual agnosias for objects, colours and faces. At six months post-stroke he demonstrated aggressive and hostile behavior, restlessness and slept poorly consistent with mania and had memory problems. There are several lines of evidence to suggest the findings could be explained as an attentional disorder. The neuropsychological features declined over a period of 14 months from mild to severe dementia. The MRI showed involvement of the right temporo-occipital regions involving
the hippocampus, mesial temporal regions and extending to involve the thalamus and the retrospenial cortex.
Conclusions: The frontal-subcortical circuitry and the frontal diencephalic brain stem system provide a comprehensive framework for the understanding of the varied and complex neuropsychological
and neurobehavioral features associated with posterior cerebral artery infarction.

Keywords: Posterior cerebral artery infarction, frontal-subcortical circuitry, frontal diencephalic brain stem system, secondary mania

Add Comment 0 Comments

23

In Press

12 Feb 2024 : Case report  Germany

Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...

Am J Case Rep In Press; DOI: 10.12659/AJCR.942870  

0:00

12 Feb 2024 : Case report  USA

Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PET

Am J Case Rep In Press; DOI: 10.12659/AJCR.941169  

0:00

12 Feb 2024 : Case report  USA

Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942839  

13 Feb 2024 : Case report  Bahrain

Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel Hematoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.943519  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

05 Mar 2022 : Case report  Brazil

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...

DOI :10.12659/AJCR.935336

Am J Case Rep 2022; 23:e935336

02 Apr 2022 : Case report  Saudi Arabia

Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...

DOI :10.12659/AJCR.935743

Am J Case Rep 2022; 23:e935743

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923