Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 March 2002

Interferon alpha in chronic hepatitis B treatment in a child with diagnosed linear IgA bullous dermatosis (LABD)

Dariusz Marek Lebensztejn, Maciej Kaczmarski, Bożena Olkowska

Case Rep Clin Pract Rev 2002; 3(1):36-39 :: ID: 475114

Abstract

Background: Interferon alpha treatment is a first choice therapy in children with chronic hepatitis caused by HBV infection.
Case report: The aim of the study was to present the IFN alpha application in chronic hepatitis as a cause of HBV superinfection in a 9-year-old child with diagnosed linear IgA bullous dermatosis (LABD). During 20-week
IFN alpha therapy we did not observe side-effects of the treatment; we observed HBeAg/antiHBe seroconversion, normalization of AlAT activity, regression of HBV DNA polymerase activity in blood serum and improvement
of skin lesions.
Conclusions: The disease history analysis of the treated boy indicates that application of IFN alpha in chronic hepatitis caused by HBV superinfection is possible in treatment of individual cases of children with autoimmunity
disorders. The clear-sighted monitoring of liver function and autoimmunity parameters are recommended.

Keywords: chronic hepatitis, HBV infection, interferon alpha, LABD, children

Add Comment 0 Comments

17

In Press

12 Feb 2024 : Case report  Germany

Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...

Am J Case Rep In Press; DOI: 10.12659/AJCR.942870  

0:00

12 Feb 2024 : Case report  USA

Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PET

Am J Case Rep In Press; DOI: 10.12659/AJCR.941169  

0:00

12 Feb 2024 : Case report  USA

Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942839  

13 Feb 2024 : Case report  Bahrain

Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel Hematoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.943519  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

05 Mar 2022 : Case report  Brazil

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...

DOI :10.12659/AJCR.935336

Am J Case Rep 2022; 23:e935336

02 Apr 2022 : Case report  Saudi Arabia

Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...

DOI :10.12659/AJCR.935743

Am J Case Rep 2022; 23:e935743

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923