ISSN 1941-5923


Get your full text copy in PDF

Rapid progression of Wegener’s Granulomatosis to therapy related Myelodysplastic Syndrome and Acute Myelomonocytic Leukemia: case report

Christos Bomboris, George Andreopoulos, Nora-Athina Viniou, Stefanos Koyndoyris, Nikolaos Kaklamanis, Maria Moschogianni, John Dalamagas, Eleni Variami, Anastasios Andreopoulos, George Vaiopoulos, John Meletis, Gerasimos Pangalis

Am J Case Rep 2008; 9:74-77

ID: 744378

Background: Treatment of Wegener’s Granulomatosis (WG) with Cyclophosphamide still remains a problem for developing secondary malignancies.
Case Report: A 64 year old patient diagnosed with WG in May 2004, developed RAEB I MDS and Acute Myelomonocytic Leukemia after treatment with relatively low dose of Cyclophosphamide 26 months after diagnosis of rheumatic disease.
Conclusions: We suggest close hematological monitoring of WG patients treated with alkylating agents for early diagnosis of secondary, therapy related, disorders.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree