Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

25 May 2009

Clearing off wisconsin solution used in liver transplantation in pediatric patients

Ahmet Mahli, Demet Coskun, Gizem Ilvan, Sema Oncul, Hakan Sozen, Aydin Dalgic

Am J Case Rep 2009; 10:72-74 :: ID: 869656

Abstract

Background: Organ preservation is an important component of transplantation process. It ensures the vitability of the donor’s organ until the time of its implantation in the receiver.
Case Report: A 7.5-month-old, 7300 gram female infant who had been diagnosed with neonatal cholestatic hepatitis at the age of one month and who had never undergone surgery before was operated on for liver transplantation. The left lobe of the liver donated by the mother was applied 500 ml of Wisconsin solution for preservation. At the end of anhepatic phase, K+ value of the receiver was 4.5 meq/L. Before the neohepatic phase, a cleansing solution of 100 ml of 20% human albumin in 1000 ml of 5% dextrose was prepared to clean the donor’s liver off University of Wisconsin (UW) solution and K+ in particular. Until the fluid drained from the donor’s liver was clear, the donor’s liver was administered 300 ml of the solution. As the washing was considered to be inadequate, this process was sustained by using 800 ml of the washing solution. The first K+ value measured after reperfusion was 5.5 meq/L. The operation was completed without any complications and no problems were encountered during the postoperative 6-month follow-up.
Conclusions: No information was found in literature regarding how much washing solution should be used to reduce the K+ burden that occurs in the receiver as a result of K+ rich UW solution which is used in order to protect the organ during liver transplantation. Organ washing procedure is conventionally extended until the washing solution becomes clear. However, in pediatric cases, we propose that the washing procedure has to be extended not until the washing solution becomes clear but until 100 ml of human albumin 20% in 1000 ml of 5% dextrose solution is used up.

Keywords: University of Wisconson (UW) solution, pediatry, liver transplantation (LTX)

Add Comment 0 Comments

In Press

12 Feb 2024 : Case report  Germany

Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...

Am J Case Rep In Press; DOI: 10.12659/AJCR.942870  

0:00

12 Feb 2024 : Case report  USA

Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PET

Am J Case Rep In Press; DOI: 10.12659/AJCR.941169  

0:00

12 Feb 2024 : Case report  USA

Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942839  

13 Feb 2024 : Case report  Bahrain

Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel Hematoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.943519  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

05 Mar 2022 : Case report  Brazil

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...

DOI :10.12659/AJCR.935336

Am J Case Rep 2022; 23:e935336

02 Apr 2022 : Case report  Saudi Arabia

Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...

DOI :10.12659/AJCR.935743

Am J Case Rep 2022; 23:e935743

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923