H-Index
12
Scimago Lab
powered by Scopus
eISSN: 1941-5923

Logo



Get your full text copy in PDF

Mediastinitis: Could your case be a candidate for candida?

Bernadette Johnson, Joshua Davis, Maria Sisneros

Am J Case Rep 2012; 13:86-88

DOI: 10.12659/AJCR.882856


Background:    Candida mediastinitis is rare, but mortality has been reported as high as 50%. There are no clinical trials evaluating treatment of Candida mediastinitis and there are only a limited number of reports in the literature.
    Case Report:    We present two cases of mediastinitis after coronary artery bypass grafting due to Candida albicans. Immunosuppression and long surgical procedures were likely risk factors for the infections. After multiple hospitalizations and debridements there was concern for the development of resistance. However, the isolates were determined to be fluconazole-susceptible and the patients were treated with long-term oral fluconazole.
    Conclusions:    Candida mediastinitis is difficult to treat. Even with appropriate treatment, patients may require numerous surgical debridements.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree