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13 September 2020 : Case report  Saudi Arabia

Prolonged Survival of a Patient with Chronic Myeloid Leukemia in Accelerated Phase with Recurrent Isolated Central Nervous System Blast Crisis

Unusual clinical course, Unusual or unexpected effect of treatment

Ahmed A. Bin Salman1ABCDEF*, Abdul Rehman Zia Zaidi12ABCDEF, Syed Yasir Altaf1E, Nawal F. AlShehry1E, Imran K. Tailor1E, Ibraheem H. Motabi1E, Syed Ziauddin A. Zaidi1ABCDEF

DOI: 10.12659/AJCR.922971

Am J Case Rep 2020; 21:e922971

Figure 3. (A–D) Composite radiological images of MRI of the brain (axial FLAIR and post gadolinium T1 WI) at second CNS relapse in February 2011. Interval improvements in signal abnormalities and leptomeningeal enhancement observed in the right posterior parietal location in images A and B were due to leukemic leptomeningeal infiltration (red circles). New non-enhancing hyperintensities in image C were more marked in the left temporopolar regions. Bilateral frontal subcortical white matter was thought to indicate new leukemic infiltrations, as these were not seen in the previous MRI (red circle).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923