Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

Christoforos Kosmidis; Nikolaos Varsamis; Stefanos Atmatzidis; Georgios Koimtzis; Stylianos Mantalovas; Georgios Anthimidis; Eleni Georgakoudi; Christina D. Sevva; Katerina Zarampouka; Danai Chourmouzi; Ariadni Leptopoulou; Sofia Baka; Maria Kosmidou

doi:10.12659/AJCR.924760

10 July 2020 : Case report Greece

Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

Challenging differential diagnosis, Rare disease

Christoforos Kosmidis^1ACDF, Nikolaos Varsamis^1ABCDEFG*, Stefanos Atmatzidis^2BCDF, Georgios Koimtzis^2ACF, Stylianos Mantalovas^2ACF, Georgios Anthimidis^1ADF, Eleni Georgakoudi^3AC, Christina D. Sevva^4FG, Katerina Zarampouka^5BCD, Danai Chourmouzi^6BCD, Ariadni Leptopoulou^7AD, Sofia Baka^3ACD, Maria Kosmidou^8DF

DOI: 10.12659/AJCR.924760

Am J Case Rep 2020; 21:e924760

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Figure 4. Histopathological images of ITPN as shown in (A) The duct is completely filled by the tubule and few papillae forming neoplasm (H&E 100×). (B) Dense packed tubules and papillae with moderate to severe nuclear atypia. Note the absence of mucin (H&E 200×). (C) ITPN below the duodenum wall (H&E 100×). (D) Focus of invasive ductal carcinoma (H&E 200×). ITPN – intraductal tubulopapillary neoplasm; H&E – hematoxylin and eosin.

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Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

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