10 July 2020: Articles
Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case
Challenging differential diagnosis, Rare disease
Christoforos Kosmidis A , Nikolaos Varsamis A* , Stefanos Atmatzidis B , Georgios Koimtzis A , Stylianos Mantalovas A , Georgios Anthimidis A , Eleni Georgakoudi A , Christina D. Sevva F , Katerina Zarampouka B , Danai Chourmouzi B , Ariadni Leptopoulou A , Sofia Baka A , Maria Kosmidou DDOI: 10.12659/AJCR.924760
Am J Case Rep 2020; 21:e924760
Figure 4. Histopathological images of ITPN as shown in (A) The duct is completely filled by the tubule and few papillae forming neoplasm (H&E 100×). (B) Dense packed tubules and papillae with moderate to severe nuclear atypia. Note the absence of mucin (H&E 200×). (C) ITPN below the duodenum wall (H&E 100×). (D) Focus of invasive ductal carcinoma (H&E 200×). ITPN – intraductal tubulopapillary neoplasm; H&E – hematoxylin and eosin.