Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

Christoforos Kosmidis; Nikolaos Varsamis; Stefanos Atmatzidis; Georgios Koimtzis; Stylianos Mantalovas; Georgios Anthimidis; Eleni Georgakoudi; Christina D. Sevva; Katerina Zarampouka; Danai Chourmouzi; Ariadni Leptopoulou; Sofia Baka; Maria Kosmidou

doi:10.12659/AJCR.924760

10 July 2020 : Case report Greece

Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

Challenging differential diagnosis, Rare disease

Christoforos Kosmidis^1ACDF, Nikolaos Varsamis^1ABCDEFG*, Stefanos Atmatzidis^2BCDF, Georgios Koimtzis^2ACF, Stylianos Mantalovas^2ACF, Georgios Anthimidis^1ADF, Eleni Georgakoudi^3AC, Christina D. Sevva^4FG, Katerina Zarampouka^5BCD, Danai Chourmouzi^6BCD, Ariadni Leptopoulou^7AD, Sofia Baka^3ACD, Maria Kosmidou^8DF

DOI: 10.12659/AJCR.924760

Am J Case Rep 2020; 21:e924760

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Figure 5. Immunohistochemical images of ITPN. (A) The tumor cells are positive for cytokeratin 7 (immunostain 200×). (B) The tumor cells are positive for CA 19-9 (immunostain 200×). (C) The tumor cells are positive for MUC1 (immunostain 200×). (D) The tumor cells are negative for cytokeratin 20 (immunostain 200×). (E) The tumor cells are negative for MUC2 (immunostain 200×). (F) The tumor cells are negative for CDX2 (immunostain 200×). ITPN – intraductal tubulopapillary neoplasm.

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Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case

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