A Patient with 22q11.2 Deletion Syndrome Presenting with Systemic Skin Rash and Dermatopathic Lymphadenitis of Unusual Histology

Yoshiro Otsuki; Hiroshi Kobayashi; Yoshifumi Arai; Nao Inoue; Tadashi Matsubayashi; Masaaki Koide; Mitsunori Yamakawa

doi:10.12659/AJCR.924961

26 August 2020 : Case report Japan

A Patient with 22q11.2 Deletion Syndrome Presenting with Systemic Skin Rash and Dermatopathic Lymphadenitis of Unusual Histology

Rare coexistence of disease or pathology

Yoshiro Otsuki^1ABCDEF*, Hiroshi Kobayashi^12ACDEF, Yoshifumi Arai^1CDEF, Nao Inoue^3BCDE, Tadashi Matsubayashi^4BCDE, Masaaki Koide^5BCDE, Mitsunori Yamakawa^6ACDEF

DOI: 10.12659/AJCR.924961

Am J Case Rep 2020; 21:e924961

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Figure 3. Microscopical features of the lymph node. (A, B) Atrophic germinal centers without mantle zone were sparsely distributed (H&E, ×15, ×30, respectively). (C) The germinal centers were surrounded by many spindle-shaped cells (H&E, ×150). (D) Fontana-Masson staining revealed many melanin particles in the macrophages (Fontana-Masson staining, ×300).

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A Patient with 22q11.2 Deletion Syndrome Presenting with Systemic Skin Rash and Dermatopathic Lymphadenitis of Unusual Histology

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