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30 August 2020: Articles

Amyloid Variant of Central Odontogenic Fibroma in the Mandible: A Case Report and Literature Review

Rare disease

Wataru Kakuguchi A* , Yoshiyuki Nakamichi E , Tetsuya Kitamura B

DOI: 10.12659/AJCR.925165

Am J Case Rep 2020; 21:e925165

Figure 5. Histopathological examination of the central odontogenic fibroma. (A, B) The tumor consisted of fibrous connective tissue with scattered epithelial islands and strands (hematoxylin and eosin stain). (C) Positive AE1/AE3 immunostaining of the tumor. (D) Positive CK5/6 immunostaining of the tumor. (E) Positive CK19 immunostaining of the tumor. (F) Negative Ki-67 immunostaining. (G–I) DSF and Congo red staining revealed amyloid deposits as homogeneous eosinophilic globular masses. (J) Observation of green birefringence under polarized light. (K, L) Positive CD1a and S-100 immunostaining of the Langerhans cells.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923