30 August 2020
: Case report 
Amyloid Variant of Central Odontogenic Fibroma in the Mandible: A Case Report and Literature Review
Rare disease
Wataru Kakuguchi1ABCDEF*, Yoshiyuki Nakamichi1E, Tetsuya Kitamura2BCDEDOI: 10.12659/AJCR.925165
Am J Case Rep 2020; 21:e925165
Figure 5. Histopathological examination of the central odontogenic fibroma. (A, B) The tumor consisted of fibrous connective tissue with scattered epithelial islands and strands (hematoxylin and eosin stain). (C) Positive AE1/AE3 immunostaining of the tumor. (D) Positive CK5/6 immunostaining of the tumor. (E) Positive CK19 immunostaining of the tumor. (F) Negative Ki-67 immunostaining. (G–I) DSF and Congo red staining revealed amyloid deposits as homogeneous eosinophilic globular masses. (J) Observation of green birefringence under polarized light. (K, L) Positive CD1a and S-100 immunostaining of the Langerhans cells.