12 August 2020
: Case report
Persistent Hyperinsulinemic Hypoglycemia with Pancreatic Teratoma in Infancy: A Case Report
Unusual clinical course, Challenging differential diagnosis
Ayse Pinar Cemeroglu1BCDEF*, Faik Sarialioglu2BCDE, Fatma Burcu Belen-Apak2BCDF, Yunus Kasim Terzi3BDEFDOI: 10.12659/AJCR.925273
Am J Case Rep 2020; 21:e925273
Figure 3. Histopathologic examination: Macroscopically, the surgical material consisted of a cystic mass with a diameter of 175×80×40 mm and a solid component with a diameter of 66×44×40 mm with a total diameter of 205×80×40 mm. (A) Pattern is that of a pancreatic tissue in early embryonic development with islets much higher in number than expected (Hematoxylene and Eosine X100 original magnification, shown in arrows). (B) Neuroendocrine islets showing extensive positivity for insulin (Anti-insulin antibody immunohistochemistry staining, ×100 original magnification, shown in arrows). (C) Neuroendocrine islets showing sparse glucagon positive cells (Anti-glucagon antibody immunohistochemistry staining, ×100 original magnification, shown in arrows).