08 September 2021
: Case report 
Histoplasmosis Related to Immunosuppression in a Patient with Crohn’s Disease: A Diagnostic Challenge
Unusual clinical course, Challenging differential diagnosis, Adverse events of drug therapy
Sandro da Costa Ferreira1ACDEF*, Fernando Jorge Firmino Nóbrega1BF, Roberta Chaves de Araújo1B, Patrícia Holanda de Almeida1B, Márcia Guimarães Villanova1B, Rodrigo de Carvalho Santana2DG, Leandra Naira Zambelli Ramalho3DG, Ana de Lourdes Candolo Martinelli1DG, Luiz Ernesto de Almeida Troncon1ADEFGDOI: 10.12659/AJCR.925345
Am J Case Rep 2021; 22:e925345
Figure 1. (A, B) Granulomatous inflammation in the liver, with the presence of clustered macrophages (H&E, 20 and 40×, magnification, respectively). (C, D) Absence of acid-fast bacilli in granulomas (Ziehl-Neelsen, 20 and 40×, magnification, respectively). (E–G) Presence of small rounded, birefringent, and clustered structures (Gomori-Methanamine-Silver, 20, 40 and 100×, magnification, respectively).