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28 July 2020: Articles

A Case of Extranodal Rosai-Dorfman Disease Presenting as an Isolated Mass on the Base of the Tongue in a 57-Year-old Woman

Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Joo Yeon Kim * , Hye-kyung Shim * , Mi Ra Kim A*

DOI: 10.12659/AJCR.925716

Am J Case Rep 2020; 21:e925716

Figure 2. Histopathologic results of the microscopic examination. (A) At low magnification, a well demarcated nodular mass is seen and there is no evidence of lymph node within the excised specimen (H&E, 12.5× magnification). (B) Extensive inflammatory cell infiltration in the subepithelial stroma (H&E, 200× magnification). (C) A mixture of numerous histiocytes, plasma cells and a few neutrophils are identified (H&E, 400× magnification). (D) Enlarged histiocytes exhibiting characteristic emperipolesis (black arrow) (H&E, 400× magnification).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923