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03 December 2020 : Case report  USA

A Fatal Case of Kaposi Sarcoma Immune Reconstitution Syndrome (KS-IRIS) Complicated by Kaposi Sarcoma Inflammatory Cytokine Syndrome (KICS) or Multicentric Castleman Disease (MCD): A Case Report and Review

Unusual clinical course, Challenging differential diagnosis, Rare disease, Rare coexistence of disease or pathology

Igor Dumic12ABCDEFG*, Milan Radovanovic12ABG, Oladapo Igandan12DEG, Ivana Savic3CDF, Charles W. Nordstrom12DEG, Djordje Jevtic4AEF, Anand Subramanian12DEG, Poornima Ramanan5CDEF

DOI: 10.12659/AJCR.926433

Am J Case Rep 2020; 21:e926433

Figure 2. In this high-power image we can observe infiltrate consisting of atypical spindled endothelial cells forming vascular channels intersecting between collagen bundles. Promontory sign (normal vessel enveloped in atypical vascular space) is present in the black box. This characteristic is not specific for KS and can also be seen in other vascular neoplasms such as angiosarcoma.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923