09 March 2021: Articles
Primary Brain Melanoma in a Pediatric Patient: A Case Report
Challenging differential diagnosis, Rare disease
Gretchen A. Otero-Soto A* , Viviana Vidal-Anaya B , Eduardo J. Labat ADOI: 10.12659/AJCR.926749
Am J Case Rep 2021; 22:e926749
Figure 5. (A) Hematoxylin & eosin (H&E) staining (magnification 20×) shows nests of melanoma cells (left) next to normal brain tissue (right). (B) H&E staining (magnification 40×) shows sheets of malignant melanocytes with prominent eosinophilic nucleoli and dense melanin pigmentation. (C) Magnification (magnification 20×) shows a positive cytoplasmic immunoreaction to HMB45 (red chromophore).