27 October 2020: Articles
Neonatal Acute Lymphoblastic Leukemia with t(9;11) Translocation Presenting as Blueberry Muffin Baby: Successful Treatment by ALL-BFM Induction Therapy, Allogeneic Stem Cell Transplantation from an Unrelated Donor, and PCR-MRD-Guided Post-Transplant Follow-Up
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Simon Schlegel A , Henning Hamm B , Alexandra Reichel B , Hermann Kneitz B , Karen Ernestus B , Oliver Andres A , Verena G. Wiegering B , Matthias Eyrich B , Matthias Wölfl B , Paul-Gerhardt Schlegel A*DOI: 10.12659/AJCR.927153
Am J Case Rep 2020; 21:e927153
Figure 3. Flow cytometry of bone marrow: Phenotype overlay of blast cells at the time of diagnosis characterized as CD19+, CD22low, CD10– (A, B; blast population in light blue ) and regenerating normal B cell compartment (A, B; normal B cell population in purple ) just prior to allogeneic stem cell transplantation. Lymphoid cells were gated in a SSC/FSC plot. The phenotype of the blast population was characterized by additional flow cytometric markers as CD45low, CD79α+, CD20–, CD34–, TdT– (data not shown). Results of phenotyping were confirmed by the national ALL reference laboratory.