18 March 2021
: Case report
Primary BRAF Mutant Melanoma of the Lung Treated with Immunotherapy and Pulmonary Bilobectomy: A Case Report
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Laura Bernal1ADE, Juliana Restrepo2ABCDEF*, Martha L. Alarcón1ABCDEF, Carlos Carvajal3BDF, Carlos E. Bonilla14ADF, Ana Maria Ramírez3ADF, Rafael Beltrán3ADFDOI: 10.12659/AJCR.927757
Am J Case Rep 2021; 22:e927757
Figure 2. (A) Malignant epithelioid-like tumor cells with prominent nucleolus, compatible with endobronchial malignant melanoma. Hematoxylin-Eosin staining on initial biopsy. (B) Tumor cells positive for HMB 45 on initial biopsy. (C) Tumor cells positive for S100 on initial biopsy. (D) Hematoxylin-Eosin staining of the surgical specimen. (E) Tumor cells positive for Melan A. (F) Tumor cells positive for SOX 10. All pathology images are 40× magnification, except for images D and E, which are 10×.






