18 December 2020>: Articles
Masked Diabetes Insipidus Hidden by Severe Hyponatremia: A Case of Pituitary Metastasis of Lung Adenocarcinoma
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy , Educational Purpose (only if useful for a systematic review or synthesis)Miki Watanabe A , Junichi Yasuda C , Kenji Ashida A* , Yuko Matsuo C , Ayako Nagayama C , Yuka Goto C , Shimpei Iwata C , Masayuki Watanabe C , Jun Sasaki B , Tomoaki Hoshino C , Masatoshi Nomura A
Am J Case Rep 2020; 21:e928113
Figure 3. Clinical course of the present case. Administration of oral and intravenous sodium chloride transiently increased the serum sodium concentration at first admission; however, fatigue and anorexia persisted. Hydrocortisone administration followed by levothyroxine replacement increased the sodium concentration up to 151 mmol/L. Desmopressin administration was required to attenuate the hypernatremia caused by the masked diabetes insipidus. Open circles with solid line represent serum sodium concentration, and closed circles with broken line represent urine specific gravity.