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18 December 2020: Articles

Masked Diabetes Insipidus Hidden by Severe Hyponatremia: A Case of Pituitary Metastasis of Lung Adenocarcinoma

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy , Educational Purpose (only if useful for a systematic review or synthesis)

Miki Watanabe A , Junichi Yasuda C , Kenji Ashida A* , Yuko Matsuo C , Ayako Nagayama C , Yuka Goto C , Shimpei Iwata C , Masayuki Watanabe C , Jun Sasaki B , Tomoaki Hoshino C , Masatoshi Nomura A

DOI: 10.12659/AJCR.928113

Am J Case Rep 2020; 21:e928113

Figure 3. Clinical course of the present case. Administration of oral and intravenous sodium chloride transiently increased the serum sodium concentration at first admission; however, fatigue and anorexia persisted. Hydrocortisone administration followed by levothyroxine replacement increased the sodium concentration up to 151 mmol/L. Desmopressin administration was required to attenuate the hypernatremia caused by the masked diabetes insipidus. Open circles with solid line represent serum sodium concentration, and closed circles with broken line represent urine specific gravity.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923