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23 June 2021: Articles

Multiple Gastric Carcinomas Associated with Epstein-Barr Virus and : A Thought-Provoking Case

Challenging differential diagnosis, Rare coexistence of disease or pathology

Tomohide Hori A* , Hidekazu Yamamoto D , Hideki Harada D , Michihiro Yamamoto D , Masahiro Yamada B , Takefumi Yazawa B , Ben Sasaki B , Masaki Tani B , Asahi Sato B , Hikotaro Katsura B , Yasuyuki Kamada B , Ryotaro Tani B , Ryuhei Aoyama B , Yudai Sasaki D , Masayuki Shintaku A , Yoko Iwasa C , Masazumi Zaima A

DOI: 10.12659/AJCR.931668

Am J Case Rep 2021; 22:e931668

Figure 5. Macroscopic findings and microscopic assessments of gastric carcinoma (GC) in the posterior wall of the gastric body. (A) Macroscopic findings from the GC in the posterior wall of the gastric body (green arrow). (B, C) Pathologic findings based on hematoxylin and eosin staining (B, ×80, C, ×200). Both moderately differentiated tubular adenocarcinomas had invaded the submucosal layer. Marked lymphocytic infiltration into the stroma was seen on in situ hybridization of EBV. (D) Immunohistochemical examination with in situ hybridization of Epstein-Barr virus (EBV) was positive for EBV-encoded small ribonucleic acid. EBV – Epstein-Barr virus, GC – gastric carcinoma.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923