11 August 2021>: Articles
A 19-Year-Old Man with a History of Recreational Inhalation of Nitrous Oxide with Severe Peripheral Neuropathy and Central Pulmonary Embolism
Unusual clinical course, Challenging differential diagnosisOliver Buchhave Pedersen C , Anne-Mette Hvas C , Erik Lerkevang Grove A*
Am J Case Rep 2021; 22:e931936
Figure 2. Schematic overview of the effect of vitamin B12 on the metabolism of methylmalonic acid and homocysteine. Nitrous oxide (N2O) oxygenates the core of vitamin B12 (B12), leading to inactivation and functional vitamin B12 deficiency. This results in elevated levels of methylmalonic acid and homocysteine.