11 August 2021
: Case report
A 19-Year-Old Man with a History of Recreational Inhalation of Nitrous Oxide with Severe Peripheral Neuropathy and Central Pulmonary Embolism
Unusual clinical course, Challenging differential diagnosis
Oliver Buchhave Pedersen12CDEF, Anne-Mette Hvas13CDE, Erik Lerkevang GroveDOI: 10.12659/AJCR.931936
Am J Case Rep 2021; 22:e931936
Figure 2. Schematic overview of the effect of vitamin B12 on the metabolism of methylmalonic acid and homocysteine. Nitrous oxide (N2O) oxygenates the core of vitamin B12 (B12), leading to inactivation and functional vitamin B12 deficiency. This results in elevated levels of methylmalonic acid and homocysteine.






