25 August 2021>: Articles
Transition From Distinct Types of Mutation-Harboring Multifocal Lung Adenocarcinoma to Rhabdoid Tumor: A Longitudinal Follow-Up
Challenging differential diagnosis, Rare disease
Kensuke Setoguchi * , Shigehisa Yanagi ** , Toshihiro Gi A , Hironobu Tsubouchi A , Kazuko Uto A , Takafumi Shigekusa A , Nobuhiro Matsumoto A , Yuichiro Sato A , Masamitsu Nakazato ADOI: 10.12659/AJCR.932452
Am J Case Rep 2021; 22:e932452
Figure 3. Immunohistochemical findings of the tumor in the right lobe of the lung. The adenocarcinoma component was positive for AE1/AE3 (A), CAM 5.2 (C), CK7 (F), and CK20 (G). Little immunopositivity for MUC5AC (H) and HNF4α (I) was observed in the adenocarcinoma lesion. The component of rhabdoid cells was positive for AE1/AE3 (B), CAM 5.2 (D), and vimentin (E). Paranuclear intracytoplasmic inclusions were strongly positive for vimentin in some of the rhabdoid cells (E, arrowheads). A–I: 200× magn.