Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

17 January 2022 : Case report  USA

Adult-Onset Diamond-Blackfan Anemia with RPL11 Gene Variation Case Report

Challenging differential diagnosis, Rare disease, Congenital defects / diseases, Rare coexistence of disease or pathology

Evida Mars-Holt12AEF, Alex Murdoch3EF, Amanda Frugoli12ABEF*, Brian Utz3E, Lynn Kong4CEF

DOI: 10.12659/AJCR.932649

Am J Case Rep 2022; 23:e932649

Figure 1. Bone marrow biopsy. (A) Bone marrow core biopsy at 10× magnification with hematoxylin and eosin staining. Normal cellularity with a predominance of myeloid cells and normal megakaryocytes. (B) Bone marrow aspirate at 20× magnification with hematoxylin and eosin staining. (C) Bone marrow core biopsy with magnification 40× with ecadherin staning. The ecadherin immunostain highlights small erythroid islands in the bone marrow core biopsy, overall decreased in number. (D) Bone marrow aspirate smear magnification 40×. This smear demonstrates predominance of myeloid. (E) Bone marrow aspirate smear magnification 100×. This smear demonstrates predominance of myeloid maturation without dysplasia and only rare erythroid precursors, consistent with erythroid hypoplasia. (F) Bone marrow aspirate smear magnification 100×. This smear demonstrates predominance of myeloid maturation without dysplasia.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923