A Case of Paroxysmal Cold Hemoglobinuria Possessing Moderate Paroxysmal Nocturnal Hemoglobinuria-Type Erythrocytes

Takeshi Sugimoto; Eri Masui; Shinya Ohata; Hideaki Goto; Takako Tomita; Hiromi Hashimoto; Yoshihiro Bouike

doi:10.12659/AJCR.933102

25 November 2021 : Case report Japan

A Case of Paroxysmal Cold Hemoglobinuria Possessing Moderate Paroxysmal Nocturnal Hemoglobinuria-Type Erythrocytes

Challenging differential diagnosis

Takeshi Sugimoto^1E*, Eri Masui^2B, Shinya Ohata^3B, Hideaki Goto^1D, Takako Tomita^2C, Hiromi Hashimoto^2F, Yoshihiro Bouike^4C

DOI: 10.12659/AJCR.933102

Am J Case Rep 2021; 22:e933102

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Figure 1. (A) The bone marrow findings from the bone marrow aspiration (×600, hematoxylin and eosin staining). Erythroid hyperplasia with megaloblastic change was observed. (B) Erythrocyte paroxysmal nocturnal hemoglobinuria (PNH) clones. Erythrocyte PNH clones are expressed as the total of Type II (partial deficiency) and Type III (complete deficiency) clones. (C) Granulocyte PNH clones. Granulocyte PNH clones are expressed as the total of Type II (partial deficiency) and Type III (complete deficiency) clones.

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A Case of Paroxysmal Cold Hemoglobinuria Possessing Moderate Paroxysmal Nocturnal Hemoglobinuria-Type Erythrocytes

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