02 December 2021
: Case report 
Gastric Adenocarcinoma of the Fundic Gland Type: A Case Report
Challenging differential diagnosis, Rare coexistence of disease or pathology
Akinari Kakumoto1BCDEF, Hajime Kuroda1ABCDEF*, Tsengelmaa Jamiyan2AEF, Takeshi Shimakawa3BD, Atsuko Masunaga1EFDOI: 10.12659/AJCR.933474
Am J Case Rep 2021; 22:e933474
Figure 1. At low magnification, a gastric adenocarcinoma of the fundic gland type (GAFG) is located in the mucosa (A). The tumor consisted of clustered tumor cells resembling chief cells and cystic glands (B). At high magnification, it is clear that the tumor contains chief cells and parietal cells ➙ (C). Immunohistochemically, the tumors are positive for MUC6 and pepsinogen-I in chief cells, H+/K+ ATPase and PDGFRα in parietal cells (D–G) and are focally strongly positive for β-catenin (H).