27 September 2021
: Case report 
Herpetic Esophagitis and Eosinophilic Esophagitis: A Potential Association
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare coexistence of disease or pathology
Rodrigo Quera1ABCDEFG*, Ligia Yukie Sassaki
2ACDF, Paulina Nuñez13ABCEF, Luis Contreras4ABCDE, Constanza Bay5ABCEF, Lilian Flores1ABCDE
DOI: 10.12659/AJCR.933565
Am J Case Rep 2021; 22:e933565
Figure 2. Distal esophagus biopsies showing: (A) eroded mucosa with viral cytopathic changes characterized by multinucleation, nuclear casting, and ground-glass nuclei (HE, 400×) and (B) positive nuclei in immunohistochemical staining for HSV (400×). (C) Middle esophageal biopsy showing squamous esophageal epithelium with numerous intraepithelial eosinophils more than 20 per high-power field, some indicated with circles, HE 200×.