03 February 2022
: Case report
Pituitary Carcinoma in a Patient with Cowden Syndrome
Challenging differential diagnosis, Rare coexistence of disease or pathology
Han Zhang1ABCDEF*, Junsiyuan Li2BCD, Ming Lee3BCD, Chi Long Ho2ABCDEFDOI: 10.12659/AJCR.934846
Am J Case Rep 2022; 23:e934846
Figure 6. Immunohistochemical staining of the resected left frontotemporal tumor of the woman with pituitary carcinoma in 2021. The tumor shows high positivity for (A) synaptophysin and (B) ACTH. This confirms the pituitary origin of the tumor. (C) Epithelial membrane antigen (EMA) is negative, thus excluding the possibility of meningioma.






