08 August 2022: Articles
A Rare Case of Synchronous Intraductal Papillary Mucinous Neoplasm-Associated Pancreatic Adenocarcinoma and Signet Ring Cell Gastric Adenocarcinoma
Rare coexistence of disease or pathology
Brittney Shupp B , Hammad Liaquat A* , Samantha Rollins B , Lisa Stoll C , Gurshawn Singh C , Roderick M. Quiros A , Ayaz Matin ADOI: 10.12659/AJCR.935242
Am J Case Rep 2022; 23:e935242
Figure 2. (A–C): H&E stain (10×) of pancreatic tissue (A) showing well-defined malignant glands (arrows). A loss of expression of DPC4 revealed by immunohistochemistry stain (10×) in (B) and weak to absent nuclear expression on CDX1 immunohistochemistry (10×) in (C) confirmed a diagnosis of pancreatic adenocarcinoma. (D–F): (D) H&E stain (20×) of gastric antral tissue showing poorly differentiated adenocarcinoma with signet ring features. (E) DPC4 immunohistochemistry stain (20×) and (F) CDX2 immunohistochemistry stain (20×) showing intact nuclear expression within the gastric carcinoma.