Figure 2. Late cerebral metastasis of melanoma presents widespread dissemination in dural matter and adjacent temporal bone, temporalis and hypodermis. (A) The extradural part grew infiltratively through the skull to subcutaneous tissue. Small melanic dots were disseminated in adjacent temporal bone, temporalis, and hypodermis (white arrows indicate the tumor). (B) Postoperative head CT scan revealed a recurrent intracranial hemorrhage in the right frontal lobe. (C) Immunohistopathology confirmed melanoma dural metastasis. The tumor cells were distinctly heterogeneous, arranged in a sheet pattern. Nuclei of tumor cells were represented by visible pigments; nuclear division could be observed easily.