Figure 1. Photomicrographs of the histopathology of the axillary lymph node in a 58-year-old man show the diagnostic features of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). (A) Low-power histology shows a nodular lymph node architecture but with no normal lymphoid follicles or germinal centers. Hematoxylin and eosin (H&E). Magnification ×10. (B) High-power histology of the lymph node shows that the normal lymph node architecture is replaced by a population of histiocytes and mature lymphocytes, with scattered single lymphocyte-predominant (LP) cells (‘popcorn’ cells), which are typical for a diagnosis of NLPHL. H&E. Magnification ×100