23 October 2022: Articles
A 60-Year-Old Woman with Primary Biliary Cholangitis and Crohn’s Ileitis Following the Suspension of Ursodeoxycholic Acid
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Mario Romeo A , Marina Cipullo A , Giorgia Iadanza A , Simone Olivieri B , Antonietta Gerarda Gravina B , Raffaele Pellegrino B , Iacopo Panarese B , Marcello Dallio A* , Alessandro Federico ADOI: 10.12659/AJCR.936387
Am J Case Rep 2022; 23:e936387
Figure 3. Photomicrograph of biopsy showing the pathological features of Crohn’s disease. (A) Biopsy of the rectal mucosa site, showing inflammatory infiltrate rich in plasma cells and eosinophils, with the presence of non-necrotizing epithelioid granuloma (black arrow) (20× magnification). (B) Biopsy of the mucosa of the left colon characterized by distorted and mucin-depleted glands, with chronic inflammatory infiltrate, rich in plasma cells and eosinophils, with activity (20× magnification). (C) Biopsy of the mucosa of the right colon with evident glandular distortion and presence of cryptic abscesses (20× magnification). (D) Biopsy of the mucosa of the transverse colon with inflammatory sparing of the glandular elements (skip lesion) (20× magnification). (E) Ileal mucosa, with rare residual villi (black arrow), with intense chronic active inflammatory infiltrate and mucosal damage (10× magnification).