16 August 2022
: Case report 
Osteolytic Lesion of the Maxilla in an Undiagnosed Multiple Myeloma Patient Identified Incidentally by Cone Beam Computed Tomography
Unusual clinical course, Challenging differential diagnosis, Rare disease
Sarah AlFarabi Ali
1EF*, Hanadi M. Khalifa1ADE, Amr Bayoumi 2A, Soulafa AlMazrooa 1ABDE, Nada O. bin Madi 1D, Sara Akeel 1E, Amal M. Sindi 1D
DOI: 10.12659/AJCR.936585
Am J Case Rep 2022; 23:e936585
Figure 4. Hematoxylin and eosin (H&E) histopathology slides. (A) H&E staining exhibited multiple areas with sheets of atypical plasma cells (10× magnification). (B) H&E plasma cells with variable sizes showing eccentric nuclei with perinuclear pale zone indicating a “zone of hoff” (bottom arrow) and binucleation of a plasma cell (top arrow) (100× magnification with oil immersion).