15 November 2022: Articles
Large Desmoid Tumor of the Pancreas: A Report of a Rare Case and Review of the Literature
Rare disease
Alexis Litchinko A , Camille Brasset A , Matthieu Tihy A , Marie-Laure Amram A , Frederic Ris A*DOI: 10.12659/AJCR.937324
Am J Case Rep 2022; 23:e937324
Figure 7. Histology findings. (A) Elongated, thin, and tapered cells of uniform appearance with pale cytoplasm and embedded in a collagenous stroma. No nuclear hyperchromasia, cytological atypia, or mitosis. Blood vessels are thin-walled with perivascular edema and vascular microhemorrhages. (B) Nuclear β-catenin staining is observed. Smooth muscle actin (SMA) was weakly positive and desmin fixation was negative. DNA sequencing revealed that the CTNNB1 (β-catenin) gene carried the p.T41A (c.121A>G) mutation.