09 September 2022
: Case report 
A 44-Year-Old Alcohol-Dependent Man Who Recovered from Central Pontine Myelinolysis with Supportive Physical Therapy
Unusual clinical course, Unusual or unexpected effect of treatment, Educational Purpose (only if useful for a systematic review or synthesis)
Makoto Tobiume1BCDE, Nami Iha2BCD, Ayako Miyahira3DE, Shingo Kariya4ADEF*DOI: 10.12659/AJCR.937389
Am J Case Rep 2022; 23:e937389
Figure 3. Schematic summarizing 2 major pathways involved in exercise-induced CNS remyelination. Physical exercise excites related neurons in the brain and promotes their myelination via axonal action potentials (white arrows). Physical exercise also stimulates secretion and increases serum levels of myelination-promoting factors that subsequently enter the CNS via blood circulation (gray arrows).