18 November 2022
: Case report
A 6-Day-Old Male Infant with Severe Hyperbilirubinemia Diagnosed with Hereditary Spherocytosis at a Tertiary Hospital in East Java, Indonesia: A Diagnostic and Management Challenge in a Developing Country
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Brigitta I.R.V. Corebima





DOI: 10.12659/AJCR.937416
Am J Case Rep 2022; 23:e937416
Figure 2. Formation of spherocytes [14]. Membrane proteins deficiency causes microvesicles formation and membrane loss. Spherocytes formed will be phagocytosed by the spleen macrophages. Reproduced with permission from Elsevier, from Robbins & Cotran Pathologic Basis of Disease, 10th edition. Kumar V, Abbas AK, Aster JC. Figure 14.2. Role of the red cell membrane skeleton in hereditary spherocytosis. In Chapter 14: Red blood cell and bleeding disorders. page 638. copyright (2021).