28 December 2022
: Case report 
A 54-Year-Old Woman with Papillary Thyroid Carcinoma Associated with Secondary Amyloid Goiter and Thyroid Lipomatosis
Challenging differential diagnosis, Rare disease
Eugénia Maria Morado da Silva1EF*, Rute Alexandra da Costa Ferreira
1E, Aluixa Rosmar Colmenares Lozada 2DE, João Manuel Sequeira Duarte 1EF
DOI: 10.12659/AJCR.938156
Am J Case Rep 2022; 23:e938156
Figure 2. (A, B) A photomicrograph of the thyroid gland showing papillary carcinoma and amyloid deposition. The thyroid gland is infiltrated by pleomorphic malignant cells with nuclear enlargement and “ground-glass” nuclei (blue arrows), nuclear grooves (black arrow), and nuclear pseudo-inclusions (red arrow). The normal background thyroid tissue is replaced by amorphous pink material with the typical appearance of amyloid. Hematoxylin and eosin stain (H&E). Objective magnification A ×400 and B ×200.