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21 January 2023: Articles

Complement-Mediated Thrombotic Microangiopathy with 10 Years of Stable Renal Function After a Year-Long Treatment with Eculizumab with Coincidental Polycystic Kidney Disease

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease

Mehul P. Dixit A* , Lucy Woolverton A , Sabahat Afshan E

DOI: 10.12659/AJCR.938367

Am J Case Rep 2023; 24:e938367

Figure 1. Patient’s laboratory values during the first year of illness. The graphs demonstrate recovery from cTMA, as indicated by improved kidney function, increased hemoglobin, and restoration of LDH back to within the normal range.cTMA – complement-mediated thrombotic microangiopathy; LDH – lactate dehydrogenase; Day 0 – nadir values at onset of the disease; Start Ecu – start of Eculizumab therapy; End HD – end of hemodialysis treatment: End Ecu – end of eculizumab treatment.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923