Figure 1. A 29-year-old female patient with VWMD. (A, B) Axial T2-weighted and fluid-attenuated inversion recovery (FLAIR) images shows diffuse and bilateral symmetrical hyperintensity in the cerebral white matter. (C) T2* gradient echo image shows a diffuse, linear, and symmetrical hypointensity in the affected white matter (short arrow). (D) Magnification of an axial GRE T2*-WI apparently reveals diffuse linear juxtacortical white matter hypointensities. (E, F) Diffusion-weighted image reveals diffuse hyperintensity without diffusion restriction on the apparent diffusion coefficient map. (G) Axial T2-WI scan reveals bilateral intraocular lens insertion for congenital cataract (blanked arrow). (H) Magnification of an axial FLAIR image shows relatively spared juxtacortical white matter in the cerebral hemisphere.