13 February 2023
: Case report
A Rare Case of Ruptured Malignant Ovarian Brenner Tumor
Rare disease
Andi Kurniadi1ABEF*, Muhammad Khalif Anfasa1ABEF, Hasrayati AgustinaDOI: 10.12659/AJCR.938680
Am J Case Rep 2023; 24:e938680
Figure 2. Microscopic findings of right ovarian tumor. (A) Condensed hyperplastic round and oval cells forming a glandular structure (arrow). The cells’ nuclei were pleomorphic, hyperchromatic, and partially vascular, with clear nuclear daughter cells and mitosis. The tumor mass partially showed squamous differentiation. The surrounding fibro-collagenous connective tissue stroma was filled with lymphocytes, dilated blood vessels, and blood. (B) Visible invasion of malignant tumor cells into the lymph vasculature. Extensive areas of necrosis were also seen. Transitional cell differentiation was seen in the cyst wall of the right ovarian tumor mass (arrow).






