03 May 2023>: Articles
A 43-Year-Old Brazilian Man with Acute Impairment of Lung Function and Pulmonary Nodules with Features of Electronic Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)
Unusual clinical course, Challenging differential diagnosisLuiz Gustavo de Carvalho Sangalli Lucas A* , Lilian Fátima Miguel Acha B , Valmir Sangalli Lucas A , Domenico Capone B
Am J Case Rep 2023; 24:e939365
Figure 2. Histopathological findings and CT image: (A) Histological sections showing lung tissue with light-colored interstitial nodules of fibroblast proliferation immersed in an extracellular edematous matrix, some of them occupying the alveolar lumen (arrows); (B) Injury to the epithelium of the terminal bronchiole with interstitial fibroblastic proliferation nodule partially occluding its lumen (plugs) (arrow); (C) Multiple light-colored fibroblastic nodules distending the septal interstitium and occupying the air spaces with atelectasis of adjacent pulmonary tissue; (D) Tomographic image obtained 2 weeks before the biopsy showing multiple centrilobular pulmonary nodules and a dense triangular elongated band based on parietal pleura assigned to atelectasis (arrow). The histological findings characterize an organizing pneumonia pattern; no infectious organisms or viral cytopathic changes were identified. CT – computed tomography.