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03 May 2023 : Case report  Brazil

A 43-Year-Old Brazilian Man with Acute Impairment of Lung Function and Pulmonary Nodules with Features of Electronic Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)

Unusual clinical course, Challenging differential diagnosis

Luiz Gustavo De Carvalho Sangalli Lucas ORCID logo1ACDEF*, Lilian Fátima Miguel Acha2BCD, Valmir Sangalli Lucas ORCID logo34ABCDE, Domenico Capone ORCID logo45BCD

DOI: 10.12659/AJCR.939365

Am J Case Rep 2023; 24:e939365

Figure 2. Histopathological findings and CT image: (A) Histological sections showing lung tissue with light-colored interstitial nodules of fibroblast proliferation immersed in an extracellular edematous matrix, some of them occupying the alveolar lumen (arrows); (B) Injury to the epithelium of the terminal bronchiole with interstitial fibroblastic proliferation nodule partially occluding its lumen (plugs) (arrow); (C) Multiple light-colored fibroblastic nodules distending the septal interstitium and occupying the air spaces with atelectasis of adjacent pulmonary tissue; (D) Tomographic image obtained 2 weeks before the biopsy showing multiple centrilobular pulmonary nodules and a dense triangular elongated band based on parietal pleura assigned to atelectasis (arrow). The histological findings characterize an organizing pneumonia pattern; no infectious organisms or viral cytopathic changes were identified. CT – computed tomography.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923