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26 May 2023: Articles

RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101

Unknown etiology, Educational Purpose (only if useful for a systematic review or synthesis)

Jessica M. Goss B* , Pamela Hair A , Parvathi S. Kumar A , Ulrich Thienel A , Kenji Cunnion A , Alexander Ellis A

DOI: 10.12659/AJCR.939803

Am J Case Rep 2023; 24:e939803

Figure 1. Extracellular myeloperoxidase (MPO) produces hypochlorous acid that causes direct tissue damage and inflammation. RLS-0071 binds to the heme ring of myeloperoxidase, inhibiting hypochlorous acid production.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923