RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101

Jessica M. Goss; Pamela Hair; Parvathi S. Kumar; Ulrich Thienel; Kenji Cunnion; Alexander Ellis

doi:10.12659/AJCR.939803

26 May 2023 : Case report USA

RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101

Unknown etiology, Educational Purpose (only if useful for a systematic review or synthesis)

Jessica M. Goss^1BCDF*, Pamela Hair^1ABCDF, Parvathi S. Kumar^1ADEF, Ulrich Thienel^1AG, Kenji Cunnion^1ACDEFG, Alexander Ellis^2AE

DOI: 10.12659/AJCR.939803

Am J Case Rep 2023; 24:e939803

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Figure 1. Extracellular myeloperoxidase (MPO) produces hypochlorous acid that causes direct tissue damage and inflammation. RLS-0071 binds to the heme ring of myeloperoxidase, inhibiting hypochlorous acid production.

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RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101

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