Successful Management of Angioinvasive Deep Fungal Infections of the Penis: A Multidisciplinary Approach with Intraoperative Frozen Margins

Gene A. Krishingner; Mahtab Forouzandeh; José A. Rodríguez; Kenan Ashouri; Kiran Motaparthi; Bristol B. Whiles

doi:10.12659/AJCR.939971

02 October 2023 : Case report USA

Successful Management of Angioinvasive Deep Fungal Infections of the Penis: A Multidisciplinary Approach with Intraoperative Frozen Margins

Challenging differential diagnosis, Rare disease

Gene A. Krishingner^1ABDEFG, Mahtab Forouzandeh^2ABE, José A. Rodríguez

^3ABE, Kenan Ashouri^1E, Kiran Motaparthi^2AE, Bristol B. Whiles^1ABDEFG*

DOI: 10.12659/AJCR.939971

Am J Case Rep 2023; 24:e939971

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Figure 3. Histologic evaluation of the penis at the time of partial penectomy. (A) Fungal invasion (top) corpora spongiosum (bottom). (B) Angioinvasion with tissue necrosis. (C) Angioinvasion highlighted with periodic acid-Schiff light-green (PAS-LG) stain. (D) Broad ribbon-like non-septate hyphae with 90-degree branching (40× magnification) with Grocott’s methenamine silver (GMS) stain.

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Successful Management of Angioinvasive Deep Fungal Infections of the Penis: A Multidisciplinary Approach with Intraoperative Frozen Margins

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