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14 December 2023: Articles

Uncommon Hematogenous Metastasis: Orbital Involvement in Uterine Cervical Cancer

Unusual setting of medical care, Rare disease

Shunichi Yamaguchi E , Mai Koizumi B , Mamoru Kakuda C , Toshiya Yamamoto A*

DOI: 10.12659/AJCR.941076

Am J Case Rep 2023; 24:e941076

Figure 2. (A, B) Uterine cervical biopsy micrographs. Most of the lesions were necrotic tissues and inflammatory exudates, with a few atypical cell clusters with large, round nuclei. The lesions were positive for high-risk human papillomavirus (HR-HPV), which encompasses HPV strains 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68. (A) Hematoxylin and eosin (H&E) 40× objective. (B) HR-HPV in situ hybridization, 100× objective. (C, D) Subcutaneous biopsy micrographs. The histology was similar to that from the uterine cervix, with positive results for HR-HPV. (C) H&E 40X objective. (D) HR-HPV in situ hybridization, 100× objective.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923