Gelatinous Pleural Effusion: A Diagnostic Challenge for Pleural Mesothelioma in an 80-Year-Old Man

Ali M. Ibnian; Obaid Ullah Khan; Richard Chan; Umesh Bangalore Lakshminarayana; Fasiha Kiran; Sarah Abed; Rahim Abbas; Ahsan Amir; Noran K. Al-Kofahi

doi:10.12659/AJCR.941263

04 October 2023 : Case report United Kingdom

Gelatinous Pleural Effusion: A Diagnostic Challenge for Pleural Mesothelioma in an 80-Year-Old Man

Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis)

Ali M. Ibnian

^12ABCDEFG*, Obaid Ullah Khan^1BCD, Richard Chan^1BCD, Umesh Bangalore Lakshminarayana^1BCD, Fasiha Kiran^1BCD, Sarah Abed^1BC, Rahim Abbas^1BCD, Ahsan Amir^1BCD, Noran K. Al-Kofahi

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DOI: 10.12659/AJCR.941263

Am J Case Rep 2023; 24:e941263

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Figure 3. Histopathology of the pleural biopsy showing atypical mesothelial proliferation, with an immunohistochemistry panel that confirm the diagnosis of mesothelioma. (A) The hematoxylin and eosin staining shows atypical mesothelial proliferation, in keeping with an epithelioid mesothelioma (×20). (B) Immunohistochemistry panel showing positive calretinin, which confirmed the diagnosis of mesothelioma (×20). (C) Immunohistochemistry panel showing negative BerEp4, which excluded the presence of pulmonary adenocarcinoma (×20).

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Gelatinous Pleural Effusion: A Diagnostic Challenge for Pleural Mesothelioma in an 80-Year-Old Man

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